Chronic Kidney Disease (CKD), is a gradual loss of renal function over a duration of months or years. It often leads to mortality and morbidity in western countries and effects 11% of the adult population. It can progress towards end-stage Renal Disease (ESRD), which has currently has no cure and requires renal replacement therapy including dialysis or renal transplantation.
CKD results from more unremitting causes such as diabetes, hypertension, chronic infection, glomerulonephritis and interstitial nephritis, vasculitis, and congenital disorders. The signs and symptoms are those associated with higher levels of blood urea and creatinine that included fatigue, fluid retention in lower limbs (edema), troubled concentration, lack of appetite, and dry and itchy skin.
The goals in nephrology are the reduction of injury, the delay of progression, or renal replacement therapy consisting of two alternatives: renal transplantation or dialysis. New therapeutic studies for tissue repair have surfaced and one of the best approach is the use of Stem Cell Treatment to reduce injury in Chronic Kidney Disease (CKD). One of this treatment involves using Mesenchymal Stem Cells (MSC), which is useful in its ability to differentiate into many types of functional cells, and anti-inflammatory properties, which could help it to become a major Stem Cell Treatment for Chronic Kidney Disease (CKD).
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