• +1 855 226 0924 USA
  • +61 2 7908 7981 AUS
  • +44 20 4525 2340 UK
  • [email protected]
  • Home
  • Treatable Conditions
    • Highlighted Treatable Conditions

      • Ataxia
      • Autism / ASD
      • Brain Injuries
      • Cerebral Palsy
      • Chronic Kidney Disease
      • Liver Cirrhosis
      • Multiple Sclerosis
    •  

      • Muscular Dystrophy
      • Spinal Cord Injury
      • Stroke
    • Visual Impairment

      • ONH / SOD
      • Optic Nerve Atrophy
      • Retinitis Pigmentosa
    • Not Listed Medical Conditions

      • Read More Here
  • Awareness
  • Testimonials
  • News
  • Contact
  • Jun
    24
    2017

    Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disease affecting nerve cells in the brain and in the spinal cord. As the disease progresses voluntary muscle action is severely compromised and the disease may cause total paralysis in its late stages.

    Some genetic mutations can lead to inherited ALS, while patients with the non-inherited form of ALS display higher than normal levels of glutamate around the nerve cells in their spinal fluid. Glutamate is a chemical messenger in the brain. This chemical imbalance in the body, with glutamate at toxic levels, invariably leads to ALS.

    A faulty immune system that attacks its own normal cells can cause the death of nerve cells also triggering ALS.  Nerve cells may also be destroyed by the collection and accumulation of abnormal forms of proteins in the cells, again triggering ALS.

     

    ALS Fact Sheet

    ALS Infographic
    Amyotrophic Lateral Sclerosis (ALS) is a neurological disease which impacts motor neurons that are involved in muscle movement throughout the body.

     

    Heredity, genetics, exposure to toxic substances and smoking are some of the primary risk factors. Treatment for ALS has centred mainly on relieving symptoms and improving the quality of life for patients. This is referred to as palliative care and relies heavily on the services of occupational, physical and speech therapists. Social workers, nutritionists and diverse caregivers also play a key role in this palliative care. Home care is also critical for the well being of the patient. Under normal circumstances this palliative care only serves to alleviate the patient’s suffering. The progression of ALS invariably leads to death.

    Promising ALS Research

    Now, however, stem cells bring new hope for persons suffering from this deadly disease. In a study conducted by the University of South Florida, researchers were able to use bone marrow stem cell transplants to repair damage to the blood-spinal cord barrier in mouse models of ALS. The studies in the mouse models demonstrated improved motor functions and nervous systems conditions. If this is successfully replicated in humans, the implications will be wide ranging as palliative care takes a secondary role and real healing takes place.

    The blood-spinal cord barrier is crucial in the development of ALS. This barrier is located between the blood circulatory system and the central nervous system. Researchers in the University of South Florida’s Centre of Excellence for Aging and Brain Repair see the repair of this blood-spinal cord barrier as a critical step in using step cells in the eventual treatment of human beings. This particular study is particularly significant because it used mice with ALS unlike previous tests which used pre-symptomatic mice. Using mice with the actual condition approximates as closely as possible the conditions (and possible reactions) of a human being with the illness.

    To conduct this study, the scientists began by using stem cells harvested from human bone marrow and intravenously transplanted these into mice modeling ALS and which were already displaying clear symptoms of the disease. Four weeks into the treatment the transplanted stem cells succeeded in differentiating and attaching to the vascular walls of many capillaries. This effectively triggered the process of blood-spinal cord barrier repair. The scientists also observed that the results from the mice which received higher doses of stem cells were noticeably enhanced.

    Stem Cells and ALS

    Stem cells have the ability to differentiate. This is the capability of the cells to develop into practically any cell type in the body. This makes them ideally suited for use in restoring function that had been lost through neurodegenerative disorders (such as ALS) or through injury. These particular stem cells differentiated into endothelial cells. These are cells which make up the inner lining of a blood vessel thereby providing a barrier between blood and spinal cord tissue.

    The result of this treatment was to delay the progression of the disease which resulted in improved motor function and increased motor neuron cell survival.

    Global Stem Cells - Contact A Stem Cell Treatment Specialist Banner

    H/T: Neuroscience News

    Global Stem Cells June 24, 2017 June 27, 2017 (6826) (0)
    Tags:
    • ALS research
    Categories:
    • Amyotrophic Lateral Sclerosis (ALS)

    About author

    Global Stem Cells
    ALS Responds to Stem Cell Therapy
← ALS, Connie, 64, USA
Could Stem Cells Offer a Cure for Multiple Sclerosis? →
Contact a Specialist

Most Viewed
Medical Tourism Makes Stem Cell Treatment Available for SCI Sufferers - Global Stem Cells
Medical Tourism Makes Stem Cell Treatment Available for SCI Sufferers
January 23, 2019 (85002)
Stem cell therapy as an alternative to a liver transplant - Global Stem Cells
Stem cell therapy as an alternative to a liver transplant
February 15, 2019 (83593)
Stem cells can heal the symptoms of traumatic brain injuries - Global Stem Cells
Stem cells can heal the symptoms of traumatic brain injuries
December 27, 2018 (83522)
Stem cell treatments for Cerebral Palsy - Global Stem Cells
Stem cell treatments for Cerebral Palsy by Unique Access Medical
November 15, 2018 (82559)
Lais Regenerative Treatment - Global Stem Cells
Cerebral Palsy, Lais, 28, Brazil
September 27, 2018 (48732)
Stem Cell Use in the Fight Against Multiple Sclerosis
Stem Cell Use in the Fight Against Multiple Sclerosis
May 30, 2016 (41315)

Contact a Stem Cell Treatment Specialist Now!

Our Patient Representatives are available to introduce and to fully explain your Stem Cell treatment options. Consult with an experienced Stem Cell doctor at no charge.

Get a Second Opinion
globalstemcells.com is owned by Unique Access Medical.
Unique Access Medical provides access to progressive, responsible healthcare to increase quality of life. Unique Access Medical partners with leading-edge, next generation treatment providers, unique products and services that are integrative, safe and effective. Unique Access Medical is not a treatment provider.
  • +1 855 226 0924
  • +61 2 7908 7981
  • +44 20 4525 2340
  • [email protected]
Recent Stem Cells News
  • Stem cell therapy as an alternative to a liver transplant
  • Medical Tourism Makes Stem Cell Treatment Available for SCI Sufferers
  • Stem cells can heal the symptoms of traumatic brain injuries
  • Stem cell treatments for Cerebral Palsy by Unique Access Medical
  • Muscular Dystrophy Treated With Stem Cells in Top Asian Clinics
Stem Cells NEWSLETTER

Enter your email address and we will send you the latest stem cells news. Your information and email records will be held in strictest confidence. We promise not to spam you!

  • English English

Copyright © 2021 | Verita Neuro Pte Ltd

  • Terms & Conditions
  • Privacy Policy
  • Cookie policy

Like all medical procedures, Stem Cell Treatments have a success and failure rate. No guarantees or claim of cures are made as to the extent of the response to the treatments promoted by globalstemcells.com. Patient reviews and testimonials on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else. This website is not intended as a substitute for the diagnosis, conventional treatments and advice of your physician. The Stem Cell Treatments promoted on this page are currently not FDA approved and not part of a FDA-regulated clinical investigation. globalstemcells.com and Unique Access Medical Pte. Ltd. educate and facilitate access to medical treatments and services for patients who have exhausted all other conventional treatment options. The promoted treatments are based on independent third party clinical evidence.

We use cookies to keep our websites easy to use and relevant to our users’ requirements and to enable us to learn which advertisements bring users to our website. We do NOT use cookies to collect any personal information about you. By continuing to browse our web pages, you agree that we may use cookies for these purposes or alternatively, you can turn them off in settings.

Global Stem Cells - Logo
Privacy Overview

This website uses cookies so that we can provide you with the best user experience possible. Cookie information is stored in your browser and performs functions such as recognising you when you return to our website and helping our team to understand which sections of the website you find most interesting and useful.

Strictly Necessary Cookies

Strictly Necessary Cookie should be enabled at all times so that we can save your preferences for cookie settings.

If you disable this cookie, we will not be able to save your preferences. This means that every time you visit this website you will need to enable or disable cookies again.

Cookie Policy

More information about our Cookie Policy